Food for Thought: The Physiological Relevance of Ghrelin and Dopamine D2 Receptor Heterodimerization in the Regulation of Appetite
نویسندگان
چکیده
Establishing whether G protein-coupled receptors (GPCRs) form physiologically relevant functional homo- and heteroligomers in vivo has been a major biochemical challenge. In this issue of Neuron, Kern et al. (2012) investigate whether the anorexigenic effects of D2 dopamine receptors may be a direct consequence of allosteric modulation by Apo-ghrelin receptors.
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عنوان ژورنال:
- Neuron
دوره 73 شماره
صفحات -
تاریخ انتشار 2012